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Since ITP targets mature platelets as they circulate through the spleen, the ‘newborn’ platelets inside bone marrow are healthy and normal. In other cases, the cause is unknown (idiopathic). Antibodies that attack the body are called autoantibodies. For reasons unknown, these infections prompt the person’s lymph tissues and spleen (an organ that helps filter the blood) to make antibodies that attack the platelets in their blood. Normally, the immune system recognises ‘self’ and doesn’t attack tissues or organs of the body.ĭoctors think that some types of viral infections trigger ITP. The body’s immune system is a specialised system of cells and chemicals that fight infections. Chronic ITP has similar symptoms to acute ITP, except that it lingers for longer than six months. chronic ITP – this ongoing form accounts for most ITP seen in adults and is far less common in children.The disease goes away by itself within two to six months Sometimes a viral infection (such as a cold) seems to trigger the condition. It is far less common in adults, who are more likely to have chronic ITP. acute ITP – this is mostly a disease of childhood, and accounts for nine out of 10 cases of ITP.Whether the platelet attack is due to antibodies and/or T cells, the result is the same – low platelet counts. Occasionally a type of white blood cell (T cells) destroy platelets in ITP. Antibodies are produced by cells of the immune system, and are normally part of our system for fighting infection. In pPeople with ITP, the body produces antibodies that attack and destroy the platelets. Latelets are cell fragments that are found in the blood and normally help the blood to clot. Immune thrombocytopenic purpura (ITP) is a rare autoimmune disorder that causes you to have low platelet levels.